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PharmaIN is focused on formulating pharmaceutical compounds
to optimize drug characteristics and target delivery to the intended
tissue or receptor site. Two proprietary, platform technologies
underpin our approach to the development of potent therapeutic products:
Protected Graft Copolymer (PGC™) and PharmaIN Reversible
Binding (PRB™).
Our technologies are paired with target molecules to achieve improved
drug profile characteristics, including the following product improvements:
- Increased bio-distribution and useful circulating half-life
- Delivery of therapeutically effective drug doses to the intended
tissue or receptor site
- Reduced toxicity
- More convenient patient treatment regimens (e.g. less frequent
dosing)
- Improved solubilization and compound stability
Our innovative drug delivery can also provide potential significant
commercial benefits:
- Differentiation from generic encroachment and potential new intellectual
property
- Streamlined regulatory approvals
- Facilitation of multiple loading/synergistic therapies (e.g. more
than one active agent or "payload" reversibly attached to carrier
molecule).
- Application to potent small molecules, peptides, and protein molecules
Proof of concept has been demonstrated in multiple model systems,
indicating compatibility with molecules and peptides for many diseases,
including cancer and diabetes, among others.
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